meat: true human diet. LDL is your friend, glycemia is the enemy.

Started by mkd, May 26, 2025, 01:04 PM

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mkd


QuoteHere's a summary of the study results and takeaways regarding a 10-year ketogenic diet in a patient with type 1 diabetes and high cardiovascular risk, as discussed in the video:
 * Improved Cardiovascular Health Despite Elevated LDL: The patient on the ketogenic diet showed remarkable cardiovascular health, with better vascular and heart measurements and no signs of atherosclerotic progression compared to individuals with type 1 diabetes of the same age and sex, and in some cases, even better than those without type 1 diabetes [17:37], [17:47], [17:54]. The patient also had a calcium score of zero [18:58]. This occurred despite early elevations in LDL cholesterol [17:08].
 * Normalized Glycemia: The ketogenic diet helped the patient achieve an average HBA1C of 5.5% over the 10-year period, which is considered normal glycemia and is rare for individuals with type 1 diabetes [17:08], [17:17].
 * Glucose as a Primary Risk Factor: The discussion emphasizes that high and variable glucose levels are the primary driving force for cardiovascular disease risk in type 1 diabetes [00:00], [06:01], [07:55]. The study reinforces the importance of glycemic control in managing cardiovascular risk in this population [07:00], [29:47].
 * LDL Not the Sole Indicator: The findings suggest that elevated LDL alone may not be the most critical factor in determining cardiovascular risk, especially when other key risk factors like glucose are well-controlled [18:03], [27:11]. The study highlights the need to consider the holistic impact of a diet on various biomarkers [24:18].
 * Potential Benefits Beyond Metabolic Disease: The advanced cardiovascular measurements used in the study are validated for the general population, suggesting that the positive impacts observed might extend beyond just managing type 1 diabetes [15:57], [16:04].
 * Importance of Longitudinal Data: This 10-year case report provides crucial longitudinal data on the effects of a ketogenic diet on cardiovascular outcomes in a high-risk population, filling a significant gap in the existing research [03:31], [20:03], [25:02].
 * Need for Informed Choices and Healthcare Guidance: The video stresses the importance of patients being informed about the primary risk factors for their conditions and having healthcare professionals who are knowledgeable and can provide guidance on therapeutic dietary interventions like carbohydrate reduction [36:42], [36:53], [37:34].
Is there anything else you'd like to know about this video?

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mkd

Quote* Normalized Glycemia: The ketogenic diet helped the patient achieve an average HBA1C of 5.5% over the 10-year period, which is considered normal glycemia and is rare for individuals with type 1 diabetes [17:08], [17:17].
 * Glucose as a Primary Risk Factor: The discussion emphasizes that high and variable glucose levels are the primary driving force for cardiovascular disease risk in type 1 diabetes [00:00], [06:01], [07:55]. The study reinforces the importance of glycemic control in managing cardiovascular risk in this population [07:00], [29:47].
 * LDL Not the Sole Indicator: The findings suggest that elevated LDL alone may not be the most critical factor in determining cardiovascular risk, especially when other key risk factors like glucose are well-controlled [18:03], [27:11]. The study highlights the need to consider the holistic impact of a diet on various biomarkers [24:18].
 * Potential Benefits Beyond Metabolic Disease: The advanced cardiovascular measurements used in the study are validated for the general population, suggesting that the positive impacts observed might extend beyond just managing type 1 diabetes [15:57], [16:04].
 * Importance of Longitudinal Data: This 10-year case report provides crucial longitudinal data on the effects of a ketogenic diet on cardiovascular outcomes in a high-risk population, filling a significant gap in the existing research [03:31], [20:03], [25:02].
 * Need for Informed Choices and Healthcare Guidance: The video stresses the importance of patients being informed about the primary risk factors for their conditions and having healthcare professionals who are knowledgeable and can provide guidance on therapeutic dietary interventions like carbohydrate reduction [36:42], [36:53], [37:34].
Is there anything else you'd like to know about this video?


SuperHoneyBadger

Keto + Intermittent fasting has been the only way my dad has been able to control his type 2 diabetes, when taken seriously. The difference is incredible: reduction of insulin shots, impressed Dr's, he can actually do housework and yardwork without getting winded. I just wish he would stick to it more often than once every 3 years.

But if a quad bypass doesn't shake up your routine, nothing likely will...
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Newbeeee™

I've said it before, but the cheap seats will lol, because $£i€n£€ :rolleyes: when investigating treatments for my Sister's glioblastoma, the person that lived the longest with it (because nobody beats it), was a guy on keto for 10 years.
At 2 years, he had regressed to "eating normal" and his next mri scan, showed "it" had returned. He immediately switched back to keto, and his next mri showed no traces....
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TheeCircle™ (EuroPeon Division)
     :cheers:    :cheers:

YoDoug

"In all my years here and on the old forum I have heard, and likely said, some pretty unhinged stuff. But congrats, you're the new leader in clubhouse."  - ghuns, 6/06/2025

neurosis

I'll go back to being a conservative, when conservatives go back to being conservative.

YoDoug

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"In all my years here and on the old forum I have heard, and likely said, some pretty unhinged stuff. But congrats, you're the new leader in clubhouse."  - ghuns, 6/06/2025

YoDoug

On the other hand, if you want the actual work of a PhD researcher and author that has been part of dozens of studies and helped thousands of patients control diabetes (I and II) though diet and lifestyle changes.

https://www.amazon.com/Mastering-Diabetes-Revolutionary-Permanently-Prediabetes-ebook/dp/B07TRJJHN2?ref_=ast_author_dp
"In all my years here and on the old forum I have heard, and likely said, some pretty unhinged stuff. But congrats, you're the new leader in clubhouse."  - ghuns, 6/06/2025

mkd

Quote from: YoDoug on May 27, 2025, 06:09 AMLOL, this study was literally one patient. ONE!
Yes, which means incredibly Higher quality info than your average study that consists of spotty questionnaires on a group
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mkd

Quote from: YoDoug on May 27, 2025, 06:19 AMOn the other hand, if you want the actual work of a PhD researcher and author that has been part of dozens of studies and helped thousands of patients control diabetes (I and II) though diet and lifestyle changes.

https://www.amazon.com/Mastering-Diabetes-Revolutionary-Permanently-Prediabetes-ebook/dp/B07TRJJHN2?ref_=ast_author_dp
Sugary fruits and tree bark couldn't possibly help diabetes and insulin resistance.

YoDoug

Quote from: mkd on May 27, 2025, 06:23 AMSugary fruits and tree bark couldn't possibly help diabetes and insulin resistance.

Until you look deeper at diabetes than just controlling blood sugar. When you do you will see that it is actually excessive saturated fat in cells that causes the cells insulin resistance.

https://nutritionstudies.org/what-causes-insulin-resistance-is-fat-the-cause-of-type-2-diabetes/
"In all my years here and on the old forum I have heard, and likely said, some pretty unhinged stuff. But congrats, you're the new leader in clubhouse."  - ghuns, 6/06/2025

mkd

Quote from: YoDoug on May 27, 2025, 06:32 AMUntil you look deeper at diabetes than just controlling blood sugar. When you do you will see that it is actually excessive saturated fat in cells that causes the cells insulin resistance.

https://nutritionstudies.org/what-causes-insulin-resistance-is-fat-the-cause-of-type-2-diabetes/
Isn't Lipotoxicity a result not a cause?

YoDoug

Quote from: mkd on May 27, 2025, 07:35 AMIsn't Lipotoxicity a result not a cause?

There is quite a bit of data and study showing the fat is the cause, not the result. Controlling blood sugar is treating the symptom not the underlaying cause. Too much free fat in the system overloads cells causing insulin resistance, diabetes. Reducing blood sugar by controlling carb and sugar intake doesn't fix the underlying issue. A state of Ketosis if done correctly can reduce that system fat overload. However there are big risks. Keto raises LDL which is not good. Long term Keto shows lean muscle loss. Long term Keto increase risks of pancreatitis, fatty liver disease, and other organs issues. Staying in Keto state is not as easy as people think. the minute your body drops out of keto the bad side effects of all that fat start.
"In all my years here and on the old forum I have heard, and likely said, some pretty unhinged stuff. But congrats, you're the new leader in clubhouse."  - ghuns, 6/06/2025

mkd

Quote from: YoDoug on May 27, 2025, 08:02 AMStaying in Keto state is not as easy as people think. the minute your body drops out of keto the bad side effects of all that fat start.
Preach it brother, all this talk about diet made me go down to the vending machine and get a Snickers. At least I get to sit the rest of the day.🫣🤡😁
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