Aging well

Started by Smit, May 08, 2025, 07:06 AM

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Smit

I thought this was an interesting piece of writing and it makes sense to me.

We have a group of people who have been on the forum for a long time so I think it's relevant to a lot of people here.

It's easier to keep what you have rather than try to build back up after you've lost it. IMHO, of course. :cheers:

A Longevity Expert's 5 Tips for Aging Well

QuoteAbout two decades ago, a California research team observed a striking phenomenon: While a majority of older adults have at least two chronic diseases, some people reach their 80s without major illness.

The researchers suspected the key to healthier aging was genetic. But after sequencing the genomes of 1,400 of these aging outliers — a cohort they called the "Wellderly" — they found almost no difference between their biological makeup and that of their peers. They were, however, more physically active, more social and typically better educated than the general public.

That genes don't necessarily determine healthy aging is "liberating," and suggests that "we can pretty much all do better" to delay disease, said Dr. Eric Topol, a cardiologist and the founder of the Scripps Research Translational Institute, which ran the Wellderly study.

Dr. Topol is a prominent molecular scientist who has published 1,300 research articles, has written multiple books and has several hundred thousand followers across social media and his newsletter. His newest book, "Super Agers: An Evidence-Based Approach to Longevity," out on Tuesday, delves into the rapidly evolving science of aging.

In the book, Dr. Topol writes that tools like biological age tests and increasingly sophisticated health risk prediction could eventually paint a clearer picture of how we're aging.

With these tools and new scientific insight into how lifestyle drives the biological breakdown that comes with age, he writes, we can now do more than ever to delay that process. While we're all more likely to get diseases like Alzheimer's, cancer and diabetes as we get older, these illnesses can develop over the course of decades — which gives us a "long runway" to try to counter them, Dr. Topol said.

Here are five strategies he recommends for aging healthier.
Take up strength training.

People who exercise regularly live longer than those who don't: Studies reliably show that physical activity reduces your risk of cancer, depression, diabetes and mortality overall.

But even Dr. Topol was surprised to learn that strength training in particular can significantly lower your risks: One meta-analysis mentioned in the book found that an hour of resistance training a week lowered subjects' mortality risk by 25 percent.

Strength training has also been linked to better sleep, higher bone density and improved mental health, compared with no exercise. While there's no magic threshold for how strong you should be to delay decline, the stronger you are, the better, Dr. Topol said.

Schedule your sleep.

Studies show that adequate sleep can reduce your risk of cancer, stroke and many other illnesses.

Committing to a consistent sleep schedule is also important. One analysis found that irregular sleep schedules increased subjects' all-cause mortality risk.

Deep sleep is especially critical for better aging, Dr. Topol said. Research suggests that people who get fewer hours of deep sleep a night are at higher risk for dementia, for instance.

While drafting "Super Agers," Dr. Topol said, he increased his deep sleep from 15 minutes to almost an hour per night over the course of a year by going to sleep at the same time each night, among other lifestyle changes. (He used a wearable sleep tracker and a smartphone app to monitor his sleep patterns.)

Most sleep aids, though, don't get you deep, restorative sleep, Dr. Topol warned. Lifestyle changes — rather than drugs or supplements — are far more likely to increase your sleep duration and quality, he said.
Bolster your mental health.

Managing stress, and improving your mental health more broadly, are critical for lowering your risk of chronic disease and mortality.

There are simple steps you can take to improve your mental health and delay disease, Dr. Topol said, such as spending time outdoors. One study found that subjects who spent at least 30 minutes a week in outdoor green spaces experienced lower rates of depression and high blood pressure.

Studies show people with active social lives typically have a lower risk of mortality and disease. The Wellderly adults in the Scripps study also tended to have rich social lives, Dr. Topol wrote in "Super Agers."
Use tests and trackers sparingly.

Many longevity influencers promote blood and saliva tests that claim to measure your biological age and can cost a hundred dollars or more. New protein analyses, not yet on the market, are intended to estimate how quickly certain organs are breaking down. Scientists are also exploring biomarker tests to predict conditions like Alzheimer's.

Dr. Topol doesn't recommend the aging tests on the market today because they're expensive and it's unclear how accurate they are. But as these tests get cheaper and more sophisticated, they could help you understand your individual risks, he said.

And while he's optimistic that some wearable devices like sleep trackers or glucose monitors can help you estimate your sleep patterns or blood sugar, there's no data suggesting that using trackers without making real lifestyle changes can meaningfully improve your health, he said.
Be wary of influencers.

Longevity enthusiasts may find themselves doing their own research, especially if their doctors aren't up to date on the latest technological advances. But popular influencers are often biased, Dr. Topol warned.

There's no reason to experiment with drugs, therapies or supplements that haven't undergone clinical trials, he said, especially when exercise, sleep, improved mental health and diet are all much more likely to extend your life and health span, he said.

"If they're hawking a supplement," he said, "I would kick them off the list of being credible."
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mowens

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"I would gladly risk feeling bad at times if it also meant that I could taste my dessert." - Data

SuperHoneyBadger

Quote from: Smit on May 08, 2025, 07:06 AMmore physically active, more social and typically better educated than the general public.
Quote from: mowens on May 08, 2025, 07:50 AMNow you tell me.

Simply be wealthy and sociable, I read! That's who fits those categories when all else is equal.

Smit

Quote from: SuperHoneyBadger on May 08, 2025, 07:55 AMSimply be wealthy and sociable, I read! That's who fits those categories when all else is equal.

You didn't read the physically active part? It's not as simple maybe but kinda a big deal.

neurosis

Look at Dick Van Dyke. He says that's what his secret is. Stay active.
I'll go back to being a conservative, when conservatives go back to being conservative.

Bucky Cornstarch

QuoteThey were, however, more physically active, more social and typically better educated than the general public.

So what it's saying is that liberals live longer?

:sofa:
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YoDoug

There is a good show/series on Netflix that looks at Blue Zones that the highest centenarians. they look at different aspects. They conclude it is a sum of these aspects, not one or the other. Diet, Activity, Spirituality, Social engagement, Family/Friends, and Purpose.

At 45 years old I was overweight - 220lbs, high cholesterol, high blood pressure, pre-diabetic, and probably more. I was slow, tired, sore, chronically inflamed, etc. I needed to change. I started training BJJ/MMA. I lost a lot of weight quickly and got down to 170 but the harsh training was not sustainable. I started to look at diet. I ended up finding that the healthiest me was eating mostly plant based. On a 100% plant based diet I got down to 165, however I didn't feel strong enough for BJJ. I then focused on heavyweight lifting and got back up to 180 but my mobility started to suffer. It has been a long series of trying different combinations of diet and training. Currently I do a mix of Running/walking, Stretching/Yoga, BJJ, and weightlifting. From week to week the mix of those varies.

As of last month at my latest checkup (51yo) all of my labs were in the range of what is considered good for young men. Cholesterol was great, A1C, fasting Glucose, BP, etc.

I'm not necessarily concerned with living to 100, I'm more concerned with quality of life. I want to be able to be active not dependent on big pharma to stay alive.   
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"In all my years here and on the old forum I have heard, and likely said, some pretty unhinged stuff. But congrats, you're the new leader in clubhouse."  - ghuns, 6/06/2025

Newbeeee™

#7
I said the other day - it's all about keeping moving!
Bike legend Sammy Miller - 92 and rides his trials bike around his grounds every day, as well as runs his museum and renovates bikes


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TheeCircle™ (EuroPeon Division)
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YoDoug

I'm pretty sure one of the keys to lasting health is not eating french fries fried in beef tallow.
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"In all my years here and on the old forum I have heard, and likely said, some pretty unhinged stuff. But congrats, you're the new leader in clubhouse."  - ghuns, 6/06/2025

Smit

Depends on who you listen to.  :hrhr:

TylerBeer

They missed the part where drinking a dark ale or stout every day is irrefutably linked to being healthy and a genius
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Smit

Quote from: TylerBeer on May 08, 2025, 12:29 PMThey missed the part where drinking a dark ale or stout every day is irrefutably linked to being healthy and a genius

Everybody pretty much already knows that don't they? :headscratch:

SuperHoneyBadger

Quote from: Smit on May 08, 2025, 01:40 PMEverybody pretty much already knows that don't they?

Hell yea, easy choice between a multivitamin(aka expensive pee) or a Guiness.

Rstewart

My mother is 78 and plays golf 4 days a week.  She fries chicken, bacon, cooks burgers two days a week, and mows the lawn.  Staying active is the way.  Eating vegan isn't shit.

Edit:  she's not liberal 😂
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YoDoug

Quote from: Rstewart on May 09, 2025, 06:06 PMEating vegan isn't shit.

My father in law turns 90 next month. He has been vegan for 13 years. Lives on his own and takes no medication. 90 > 78, my anecdotal story beats yours.  ;)
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"In all my years here and on the old forum I have heard, and likely said, some pretty unhinged stuff. But congrats, you're the new leader in clubhouse."  - ghuns, 6/06/2025